Gold induced enterocolitis.

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Gold induced enterocolitis.

A case of gold associated enterocolitis is described. A review of all 27 previously reported cases revealed that the syndrome induced has common characteristics. The reaction occurs within three months of instituting gold therapy, is characterised by profuse diarrhoea and vomiting with abdominal pain, fever, and sometimes eosinophilia. Petechial changes are prominent on endoscopy and the endosc...

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Gold induced enterocolitis complicated by cytomegalovirus infection: a previously unrecognised association.

Enterocolitis is a rare complication of treatment with gold salts. It was first described in 1935 by Goldhammer2 and since then only 21 cases have been described.>"7118 The mechanism is unclear. An appreciable proportion of these cases was associated with high morbidity and mortality.4 781' Different treatment regimes including intensive supportive care with a combination of antibiotics, steroi...

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A lethal enterocolitis was induced in hamsters by oral or parenteral administration of clindamycin in amounts comparable to those used in treatment of humans. The intestinal lesions were characterized histologically as an acute inflammatory reaction with pseudomembrane formation and resembled the lesions seen in humans with antibiotic-induced colitis. Results of quantitative stool cultures show...

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ژورنال

عنوان ژورنال: Gut

سال: 1986

ISSN: 0017-5749

DOI: 10.1136/gut.27.4.452